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Assay Development Scientist
2 days ago
CY Partners London, United Kingdom**Assay Development Scientist - Virology / Immunology** · **Permanent position** · **£36,000 to £42,000 annually** · **Based in Central London** · Do you have a background in Virology and/or Immunology Assay Development? · Would you like to work for a leading clinical research or ...
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ProtonDx London, United Kingdom Full timeProtonDx is a dynamic and innovative Imperial College London spin-out, specialising in medical diagnostics and related technologies. With the recent launch of our regulatory-approved Point-of-Care Diagnostic product, Dragonfly, and a nucleic acid extraction kit for research use, ...
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Assay Scientist
1 day ago
Hyper Recruitment Solutions Ltd London, United KingdomWe are currently looking for an Assay Scientist - Enzymology/Biocatalysis to join a growing Biotechnology company based in the London area focused on revolutionising the synthesis of biomolecules through the development of immobilized enzyme cascade reactions.As the Assay Scienti ...
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Genetic Technologist
4 days ago
Synnovis London, United KingdomAn opportunity has arisen for a Genetic Technologist with a passion for developing new molecular assays. The post is for one year in the first instance, funded by Synnovis Innovation to support the laboratory's development of new tests to expand the service delivery repertoire of ...
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Moderna London, United Kingdom**The Role**: · Moderna is seeking an experienced Bioanalytical and Molecular Sciences expert to join the Clinical Bioanalytical team to lead Immunogenicity and LBA-based bioanalysis under GLP/GcLP compliance. A successful incumbent will provide Scientific and operational oversig ...
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Plrs- Pharmacology Expert
1 week ago
Francis Crick Institute London, United Kingdom**PLRS- Pharmacology Expert**: · - Employer- Francis Crick Institute- Location- London (Central), London (Greater) (GB)- Salary- From £58,000 with benefits, depending on skills and experience- Closing date- 26 May 2024- Discipline · Chemistry · Job Type · Researcher · Employment ...
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Moderna London, United Kingdom**The Role**: · Moderna is seeking a talented, experienced, and motivated Associate Director to join the UK Clinical Biomarker Laboratory to serve as a scientific expert and point of contact for the oversight of Immunoassay development, validation, and clinical testing adhering t ...
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Analytical Chemist
2 days ago
CK GROUP London, United KingdomCK Group are recruiting for an Analytical Chemist - Biocatalysis, to join a biotechnology company based in London on a permanent basis. · **The Company**: · Our client is on a mission to transform industrial chemical processes using cell-free biomanufacturing to empower users wit ...
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Analytical Chemist
1 week ago
CK GROUP London, United KingdomCK Group are recruiting for an Analytical Chemist to join a biotechnology company based in London on a permanent basis. · **The Company**: · Our client is on a mission to transform industrial chemical processes using cell-free biomanufacturing to empower users with the world's mo ...
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Principal Analytical Scientist Bioassay
6 hours ago
Hyper Recruitment Solutions Ltd London, United KingdomThis is a great opportunity to further sharpen your leadership skills and be a direct line manager scientists within your team. Additionally you'll be a part of the CMC team and work collaboratively with the research and clinical teams as well as external collaboratorsensuring th ...
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Laboratory Associate, Human Immunology Lab
1 week ago
United Kingdom London, United Kingdom**Position Description** · **Job Title**: Laboratory Associate · **Location**: Human Immunology Lab (HIL), London · **Reporting to**:Senior Manager, Clinical Immunology · **Position Summary**: · **Key Responsibilities**: · - Process clinical and research samples to a very high st ...
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Technical Lead
6 hours ago
Synnovis Analytics London, United KingdomDuties and Responsibilities The post holder will develop new tests to the point of service entry to include complete validation and verification according to ISO15189 standards. The new testing methods may include DNA extraction from a variety of sources, PCR based assays for mol ...
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Assay Specialist and Trial Lead
6 days ago
Lindus Health London, United Kingdom**About Us**: · Healthcare is in crisis: all new medicines need to undergo clinical trials to show they're safe and effective. But today's clinical trial infrastructure is stuck in the past, and the cost of developing new medicines has skyrocketed as a result. Patients have to wa ...
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Gpcr Pharmacologist
1 week ago
CK GROUP London, United KingdomCK Group are working in partnership with Avacta to recruit a GPCR Pharmacologist - Senior Scientist to be based at their state of the art facilities in West London on a permanent basis. · **About Avacta**: · Avacta is a healthcare group developing innovative cancer drugs and powe ...
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Molecular Biologist
4 days ago
UK Health Security Agency London, United KingdomThe Molecular Biologist / FCL Laboratory Manager post will work within the Microbiology team at UK-PHRST to deliver the operational diagnostics, research, and capacity strengthening objectives to partners in ODA-eligible countries, in line with the priorities identified by the Le ...
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Quality Support Technical Validation
1 week ago
UK Health Security Agency London, United Kingdom**Responsibilities section**: The job holder will be required to carry out the following responsibilities, activities and duties: To take responsibility for the routine surveillance of RSV and influenza viruses section of the RVU according to relative priorities set by the unit t ...
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Laboratory Team Lead
3 days ago
CY Partners London, United Kingdom**Laboratory Team Lead - Clinical Research** · **Permanent Position** · **£40,000 to £45,000 annually** · **Based in Central London** · Are you a Virologist, Immunologist or Biomedical Scientist with experience in Laboratory Leadership and People Management? · Would you like to w ...
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Associate Director, Bioanalytical Sciences
1 week ago
Moderna London, United Kingdom**The Role**: · Moderna is seeking an experienced Bioanalytical and Molecular Sciences expert to join the Pre Clinical and Clinical Bioanalytical team to lead LC-MS based bioanalysis under GLP/GcLP compliance. A successful incumbent will provide Scientific and operational oversig ...
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Quality Controller
1 day ago
De Beers Group of Companies London, United Kingdom**_Company Description · - You'll make us shine _** · You communicate easily and openly with your colleagues and enjoy being part of a talented and diverse team. Whether creative or analytical, you are attracted by our fascinating product: nature's hardest substance yet most tend ...
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Medical Laboratory Assistant
4 days ago
Synnovis London, United KingdomWe are looking for a Medical Laboratory Assistant (MLA) to join our expanding team. The purpose of this post is to support the service primarily through contributing to the laboratory work undertaken in the Liver Molecular Genetics laboratory. This is a permanent, full time post ...
Senior Scientist: Molecular Assay Development - London, United Kingdom - ProtonDx
Description
ProtonDx is a dynamic and innovative Imperial College London spin-out, specialising in medical diagnostics and related technologies.With the recent launch of our regulatory-approved Point-of-Care Diagnostic product, Dragonfly, and a nucleic acid extraction kit for research use, SmartLid, we are poised for rapid growth and expansion into new product lines and strategic partnerships.
We are committed to pushing the boundaries of science and technology to improve healthcare outcomes.We are looking for a Senior Scientist with significant experience in the design, development, and evaluation of molecular assays, ideally in the context of isothermal amplification chemistries, including LAMP.
KEY RESPONSIBILITIES:
Develop and validate highly sensitive and specific in vitro molecular assays (including LAMP) for the detection of pathogens associated with humans, animals, plants and other areas.
Experienced on phylogenetic/genomic analysis for comparative analysis of the specificity (inclusivity and exclusivity) of the designed molecular assays. Contribute to scientific R&D projects through hands-on design, execution, and analysis of laboratory experiments.Conducting regular in silico analysis and reports of designed assays against evolving target pathogens, including design and maintenance of necessary bioinformatics tools, and reporting.
Resolve complex technical challenges in line with clinical diagnostic assay requirements, while adhering to published regulatory standards and guidance. Accurately record and present scientific results through the completion of laboratory records, written reports, and presentations. Preparation and QC of master mixes and reagents for production of CE-marked and RUO products. Undertake additional ad hoc / project work as required. RequirementsPhD in a relevant life science discipline such as Microbiology, Genomics, Molecular Biology, or Biochemistry.Significant experience (5+ years) in molecular assay development and optimisation, particularly in the context of LAMP, and ideally within an IVD / diagnostics industry environment.
Experience in relevant laboratory techniques including:
PCR, LAMP, and nucleic acid extraction and optimization; processing biological samples. Experience working to strict quality standards and in regulated environments (ISO 13485, UK MDR, IVDR, etc.). A solid understanding of bioinformatics tools and methodologies, expertise in using computational methods to analyse genetic sequences. Experience leading projects and independently delivering against agreed timescales and outputs. An agile mind-set, happy working within a fast-moving R&D environment with evolving priorities. Excellent communication skills and a personable nature to support relationship building within the team and with key stakeholders.
Laboratory experience in the following areas would be desirable:
working in a regulated environment; infectious disease and antimicrobial resistance; precision serial dilutions; DNA sequencing; working with a containment level 2 facility; using automated molecular diagnostic systems; next generation sequencing; advanced multiplex applications; digital PCR.
Experience line managing and/or leading /mentoring small teams would be beneficial although not essential.Reports to:
Head of Product Development & CSO