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    Senior Research Fellow/Research Fellow - London, United Kingdom - UCL Eastman Dental Institute

    UCL Eastman Dental Institute
    UCL Eastman Dental Institute London, United Kingdom

    1 week ago

    Default job background
    Permanent
    Description

    About the role

    We are advertising an exciting 3 year postdoctoral position in epidemiology/data science, focusing on understanding how and when apolipoprotein E (apoE) influences the development of Alzheimer's disease (AD). The post holder will primarily use metabolomic, proteomic, genetic and biomedical data from a series of longstanding cohorts, including half a million participants of UK Biobank, and eight decades of data collected by the British Birth Cohort (coordinated from the MRC LHA) and its neurological sub-study Insight 46. The research will include use of novel dementia fluid- and neuroimaging-based biomarkers. Analyses will be multi-faceted and involve conventional association analyses alongside genetic epidemiological methods (such as Mendelian randomisation) to strengthen knowledge of the relationships between apoE, circulating molecular analytes and AD. There will also be scope to contribute to, or develop your own, research projects within the wider remit of our research units. The post is funded for 3 years. Appointment will be made on Grade 7 (£42, - £50, including London Allowance) or Grade 8 p38 (£51, only including London Allowance) subject to experience. An appointment cannot be made above G8 point 38.

    About you

    The candidate will have a PhD or equivalent work experience in epidemiology, biostatistics, bioinformatics/data science or a related population health science. If working towards a PhD, they can be close to completion of this degree. If a PhD is not yet awarded at the start date, appointment will be at Research Assistant grade 6B £37, - £39, inclusive of London Weighting per annum, with payment at grade 7 backdated to the date of submission of the final PhD thesis. The candidate is expected to have a wealth of past experience using data from population-based cohorts or equivalent experience ( statistical genetics). Experience of using complex data from genomics or -omics platforms is desirable, and essential for appointment at grade 8. Knowledge of and enthusiasm for Alzheimer's disease research is also desired. Experience of publishing empirical research findings. Excellent analytic skills, including statistical analysis and data handling. Evidence of proficiency in relevant computer packages for quantitative data analyses ( Stata, R, Python) are also expected.

    What we offer


    • 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
    • Additional 5 days' annual leave purchase scheme
    • Defined benefit career average revalued earnings pension scheme (CARE)
    • Cycle to work scheme and season ticket loan
    • Immigration loan
    • Relocation scheme for certain posts
    • On-Site nursery
    • On-site gym
    • Enhanced maternity, paternity and adoption pay
    • Employee assistance programme:Staff Support Service
    • Discounted medical insurance

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