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    Junior Project Manager - Slough, Berkshire, United Kingdom - UCB S.A.

    UCB S.A.
    UCB S.A. Slough, Berkshire, United Kingdom

    1 week ago

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    Description

    We are looking for a DMPK Project Representative who is curious and innovative to join us in ourQuantitative Discovery & Developmentteam, based at our research site in Slough, UK or Braine L'Alleud, Belgium .

    The DMPK project representative is a critical role in our R&D activities, and we are looking to recruit a senior individual with expertise in discovery and development DMPK science, preferably covering multiple modalities beyond NCE including TPD, ASO and peptides.

    The individual will have project responsibility for early discovery towards candidate selection and into the clinical phases of the development.

    They will be responsible for the project aspects of nonclinical DMPK including in vitro and in vivo activities, pre-clinical PK, translational PK and PK-PD, biotransformation and bioanalysis contributions to projects to fulfil internal and regulatory requirements up to and including registration.

    Design appropriate experimental studies and liaise with other areas of the R&D organization to deliver data and interpretations to support the project towards candidate selection and beyond
    Work with the project and Development Sciences colleagues to resolve or risk-mitigate project-related ADME challenges
    Work with other areas in the DMPK organization to champion new, innovative approaches to project support and ensure UCB stays at the forefront of DMPK science
    Prepare the DMPK sections of internal and regulatory documents (e.g. Provide scientific mentorship to support junior staff in their personal development
    PhD (or equivalent) in Pharmaceutics, Pharmacology, Drug metabolism or Pharmacokinetics, with
    7 years of Post-Doctoral Industrial experience; 10 years industrial experience in DMPK science.
    A c omprehensive understanding of discovery and development DMPK including modelling and simulation and a proven ability to delineate the impact of chemical structure on measured properties
    Wide experience in pharmaceutical R&D including a knowledge of the regulatory requirements and experience working with regulatory agencies to fulfil the DMPK contribution to new drug submissions
    A recognized track record of experience in DMPK/ADME and excellent knowledge in ADME/Enzymology/Drug Transporters and knowledge of how to couple data to optimization/selection of NCE, both in discovery and development
    UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.
    Learn more about sustainability at UCB and how it is integrated into our business approach.

    UCB and its subsidiaries encourage diversity and inclusion in the workplace; We do not discriminate on the basis of race/colour/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

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